Thapsigargin-induced activation of Ca2+-CaMKII-ERK in brainstem contributes to substance P release and induction of emesis in the least shrew - ScienceDirect
Endoplasmic reticulum stress signals in the tumour and its microenvironment | Nature Reviews Cancer
Differential impact of imipramine on thapsigargin- and tunicamycin-induced endoplasmic reticulum stress and mitochondrial dysfunction in neuroblastoma SH-SY5Y cells - ScienceDirect
Thapsigargin: key to new host-directed coronavirus antivirals?: Trends in Pharmacological Sciences
Effect of endoplasmic reticulum calcium on paraquat‑induced apoptosis of human lung type II alveolar epithelial A549 cells
Revealing Protein Aggregates under Thapsigargin-Induced ER Stress Using an ER-Targeted Thioflavin | ACS Sensors
Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation: Molecular Therapy - Oncolytics
ER-phagy: mechanisms, regulation, and diseases connected to the lysosomal clearance of the endoplasmic reticulum | Physiological Reviews
Pancreatic INS-1 β-Cell Response to Thapsigargin and Rotenone: A Comparative Proteomics Analysis Uncovers Key Pathways of β-Cell Dysfunction | Chemical Research in Toxicology
The SERCA pump as a therapeutic target: Making a “smart bomb” for prostate cancer
Current understanding of imeglimin action on pancreatic β‐cells: Involvement of mitochondria and endoplasmic reticulum homeostasis - Fauzi - 2023 - Journal of Diabetes Investigation - Wiley Online Library
From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development | SpringerLink
Frontiers | The Cross-Links of Endoplasmic Reticulum Stress, Autophagy, and Neurodegeneration in Parkinson's Disease
Cell death induced by the ER stressor thapsigargin involves death receptor 5, a non-autophagic function of MAP1LC3B, and distinct contributions from unfolded protein response components | Cell Communication and Signaling | Full Text
Chemical Specifications
Activation of p42/p44 Mitogen-Activated Protein Kinase and Contraction by Prostaglandin F2α, Ionomycin, and Thapsigargin in Cat Iris Sphincter Smooth Muscle: Inhibition by PD98059, KN-93, and Isoproterenol | Journal of Pharmacology and Experimental
Promising therapeutic effect of thapsigargin nanoparticles on chronic kidney disease through the activation of Nrf2 and FoxO1 - Figure f8 | Aging
Cells | Free Full-Text | Calcium Pathways in Human Neutrophils—The Extended Effects of Thapsigargin and ML-9
Thapsigargin induces apoptosis when autophagy is inhibited in HepG2 cells and both processes are regulated by ROS-dependent pathway - ScienceDirect
Peptide–drug conjugate-based novel molecular drug delivery system in cancer: Trends in Pharmacological Sciences
Cholesterol-Induced Phenotypic Modulation of Smooth Muscle Cells to Macrophage/Fibroblast–like Cells Is Driven by an Unfolded Protein Response | Arteriosclerosis, Thrombosis, and Vascular Biology
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